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The definition of fatigue

Synonyms:	languor, jiggered (informal), tired, lethargy, weary, ennui, heavy, debility, listless, tire, exhaust, weaken, drain, whack (Brit. informal), wear out, jade, poop (informal), knacker (slang), bushed (informal), wasted, all in (slang), jaded, knack (slang), clapped out (Austral. N.Z. informal), zonked (slang), dead beat (informal)
Antonyms:	fresh, refresh

From Collins